Before the Age of the Railway, one of the main routes to the west, from Paris, by horse drawn carriage, was via Chartres and then along the valley of the Loir river through Chateadun and Vendôme to Tours.
However the first railway line from Paris to Tours was built via Orléans thus isolating the agricultural communities of the Beauce, who had to wait thirty years before finally being connected by rail on 29th December 1865.
On that date, the new line from Brétigny to Vendôme was opened, and the region could be reached by rail from Paris.
In August 1867, the line was completed from Vendôme to Tours and made double track from Brétigny to Tours.
The war with Prussia in 1870/71 caused damage to three new bridges during the retreat from Paris.
Thereafter, the line saw much activity with a peak between 1919 and 1934, when it was used as an alternate route for expresses to the west and south-west of France.
The electrification of Paris - Orléans - Tours ended the regular use of the line for long distance traffic.
The line was singled in 1953.